Recombinant Human STAT1, E. coli

Artikelnummer: EKL-PEH1567
Artikelname: Recombinant Human STAT1, E. coli
Artikelnummer: EKL-PEH1567
Hersteller Artikelnummer: PEH1567
Alternativnummer: EKL-PEH1567-10UG,EKL-PEH1567-50UG,EKL-PEH1567-500UG
Hersteller: EnkiLife
Wirt: E. coli
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Alternative Synonym: Signal Transducer and Activator of Transcription 1-Alpha/Beta, Transcription Factor ISGF-3 Components p91/p84, STAT1
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.
Molekulargewicht: 83.3 KDa
NCBI: 42224
Reinheit: Greater than 95% as determined by reducing SDS-PAGE
Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.