Recombinant Human STAT1, E. coli

Product Overview

• Article Name: Recombinant Human STAT1, E. coli
• Biozol Catalog Number: EKL-PEH1567
• Supplier Catalog Number: PEH1567
• Alternative Catalog Number: EKL-PEH1567-10UG,EKL-PEH1567-50UG,EKL-PEH1567-500UG
• Manufacturer: EnkiLife
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Signal Transducer and Activator of Transcription 1-Alpha/Beta, Transcription Factor ISGF-3 Components p91/p84, STAT1

Product Description

Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.

Product Properties

• Molecular Weight: 83.3 KDa
• NCBI: 42224
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.