Necrox-2(TM)

Artikelnummer: ENZ-ALX-430-166-M001
Artikelname: Necrox-2(TM)
Artikelnummer: ENZ-ALX-430-166-M001
Hersteller Artikelnummer: ALX-430-166-M001
Alternativnummer: ENZ-ALX-430-166-M001-1
Hersteller: Enzo Life Sciences
Kategorie: Sonstiges
Alternative Synonym: [5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(1-methanesulfonyl-piperidin-4-yl)-amine
Cell permeable necrosis inhibitor with antioxidant activity. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1µM NecroX(TM)-2 prevented ~50% cell death in H9C2 cells exposed to 400µM t-BuOOH for 2
Molekulargewicht: 516.7
Reinheit: 95% (NMR, LCMS)
Formel: C25H32N4O4S2
Anwendungsbeschreibung: For in vitro applications, dissolve in DMSO to 20-50mM stock solution and dilute further in cell culture media. Treat cells with 30µM to 0.1µM final concentration.Optimal conditions must be determined individually for each application.