CD1d belongs to CD1 family of transmembrane glycoproteins, associated with beta2 microglobulin, similarly to MHC I molecules. Unlike other CD1 family members, however, CD1d can be also expressed in a non-glycosylated form, which is not associated with beta2 microglobulin. Hence it is not certain how much CD1d plays a role in the presentation of microbial lipid antigens during infection. On the other hand, it is expressed on various antigen presenting cell types. Besides it, CD1d+ thymocytes are involved in the positive selection of sublineage of NKT cells.
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Klon-Bezeichnung:
[51.1]
Isotyp:
Mouse IgG2b kappa
Puffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target-Kategorie:
CD1d
Antibody Type:
Monoclonal Antibody
Application Verdünnung:
Flow cytometry: Recommended dilution: 4-8 µg/ml.
Anwendungsbeschreibung:
Flow cytometry: Recommended dilution: 4-8 µg/ml.
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