CD1d belongs to CD1 family of transmembrane glycoproteins, associated with beta2 microglobulin, similarly to MHC I molecules. Unlike other CD1 family members, however, CD1d can be also expressed in a non-glycosylated form, which is not associated with beta2 microglobulin. Hence it is not certain how much CD1d plays a role in the presentation of microbial lipid antigens during infection. On the other hand, it is expressed on various antigen presenting cell types. Besides it, CD1d+ thymocytes are involved in the positive selection of sublineage of NKT cells.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[51.1]
Isotype:
Mouse IgG2b kappa
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target:
CD1d
Antibody Type:
Monoclonal Antibody
Application Dilute:
Flow cytometry: Recommended dilution: 4-8 µg/ml.
Application Notes:
Flow cytometry: Recommended dilution: 4-8 µg/ml.
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