Anti-Hu CD170 PE, Clone: [1A5], Monoclonal

Produktübersicht

• Artikelname: Anti-Hu CD170 PE, Clone: [1A5], Monoclonal
• Artikelnummer: EXB-1P-156-T100
• Hersteller Artikelnummer: 1P-156-T100
• Alternativnummer: EXB-1P-156-T100
• Hersteller: EXBIO
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human, Primate
• Immunogen: Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1
• Konjugation: PE

Produktbeschreibung

CD170, also known as Siglec 5 (sialic acid binding Ig-like lectin 5) is a type 1 transmembrane glycoprotein containing two cytoplasmic immunoreceptor tyrosine inhibitory motifs (ITIMs). CD170 forms homodimers and functions as an inhibitory receptor able to downregulate cell activation. It binds to alpha2,3- and alpha2,6-linked sialic acid ligands, e.g. on glycophorin A (CD235a). Aberrant expression of CD170 by CD34+ progenitor cells can be observed in case of acute myeloid leukemias.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [1A5]
• Isotyp: Mouse IgG1
• Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Lagerung: 2°C to 8°C
• Target-Kategorie: CD170
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.