Anti-Hu CD170 PE, Clone: [1A5], Monoclonal

Product Overview

• Article Name: Anti-Hu CD170 PE, Clone: [1A5], Monoclonal
• Biozol Catalog Number: EXB-1P-156-T100
• Supplier Catalog Number: 1P-156-T100
• Alternative Catalog Number: EXB-1P-156-T100
• Manufacturer: EXBIO
• Category: Antikörper
• Application: FC
• Species Reactivity: Human, Primate
• Immunogen: Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1
• Conjugation: PE

Product Description

CD170, also known as Siglec 5 (sialic acid binding Ig-like lectin 5) is a type 1 transmembrane glycoprotein containing two cytoplasmic immunoreceptor tyrosine inhibitory motifs (ITIMs). CD170 forms homodimers and functions as an inhibitory receptor able to downregulate cell activation. It binds to alpha2,3- and alpha2,6-linked sialic acid ligands, e.g. on glycophorin A (CD235a). Aberrant expression of CD170 by CD34+ progenitor cells can be observed in case of acute myeloid leukemias.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [1A5]
• Isotype: Mouse IgG1
• Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage: 2°C to 8°C
• Target: CD170
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Dilute: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.