Anti-Hu CD243 Alexa Fluor 647, Clone: [UIC2], AF647, Monoclonal

Produktübersicht

• Artikelname: Anti-Hu CD243 Alexa Fluor 647, Clone: [UIC2], AF647, Monoclonal
• Artikelnummer: EXB-A6-764-T100
• Hersteller Artikelnummer: A6-764-T100
• Alternativnummer: EXB-A6-764-T100
• Hersteller: EXBIO
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human
• Immunogen: NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
• Konjugation: AF647

Produktbeschreibung

CD243, also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. It is expressed in many tissues, including the brain, liver, pancreas, testes, kidney, and blood (B, T, NK cells, but not monocytes).

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [UIC2]
• Isotyp: Mouse IgG2a kappa
• Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Lagerung: 2°C to 8°C
• Target-Kategorie: CD243
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.