Anti-Hu CD243 Alexa Fluor 647, Clone: [UIC2], AF647, Monoclonal

Product Overview

• Article Name: Anti-Hu CD243 Alexa Fluor 647, Clone: [UIC2], AF647, Monoclonal
• Biozol Catalog Number: EXB-A6-764-T100
• Supplier Catalog Number: A6-764-T100
• Alternative Catalog Number: EXB-A6-764-T100
• Manufacturer: EXBIO
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Immunogen: NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
• Conjugation: AF647

Product Description

CD243, also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. It is expressed in many tissues, including the brain, liver, pancreas, testes, kidney, and blood (B, T, NK cells, but not monocytes).

Product Properties

• Clonality: Monoclonal
• Clone Designation: [UIC2]
• Isotype: Mouse IgG2a kappa
• Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage: 2°C to 8°C
• Target: CD243
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Dilute: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.