Anti-Hu CD271 PerCP-Cy5.5, Clone: [NGFR5], Monoclonal

Produktübersicht

• Artikelname: Anti-Hu CD271 PerCP-Cy5.5, Clone: [NGFR5], Monoclonal
• Artikelnummer: EXB-T9-642-T100
• Hersteller Artikelnummer: T9-642-T100
• Alternativnummer: EXB-T9-642-T100
• Hersteller: EXBIO
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Feline, Ferret, Human, Primate, Rabbit
• Immunogen: Purified CD271 protein isolated from human melanoma cell line A875
• Konjugation: PerCP/Cy5.5

Produktbeschreibung

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [NGFR5]
• Isotyp: Mouse IgG1
• Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Lagerung: 2°C to 8°C
• Target-Kategorie: CD271
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Extracellular and intracellular staining.