Anti-Hu CD271 PerCP-Cy5.5, Clone: [NGFR5], Monoclonal

Catalog Number: EXB-T9-642-T100
Article Name: Anti-Hu CD271 PerCP-Cy5.5, Clone: [NGFR5], Monoclonal
Biozol Catalog Number: EXB-T9-642-T100
Supplier Catalog Number: T9-642-T100
Alternative Catalog Number: EXB-T9-642-T100
Manufacturer: EXBIO
Category: Antikörper
Application: FC
Species Reactivity: Feline, Ferret, Human, Primate, Rabbit
Immunogen: Purified CD271 protein isolated from human melanoma cell line A875
Conjugation: PerCP/Cy5.5
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
Clonality: Monoclonal
Clone Designation: [NGFR5]
Isotype: Mouse IgG1
Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage: 2°C to 8°C
Target: CD271
Antibody Type: Monoclonal Antibody
Application Dilute: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Extracellular and intracellular staining.