GF-109203X, CAS [[133052-90-1]]

Produktübersicht

• Artikelname: GF-109203X, CAS [[133052-90-1]]
• Artikelnummer: FBM-10-1026
• Hersteller Artikelnummer: 10-1026
• Alternativnummer: FBM-10-1026-5MG, FBM-10-1026-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide. Alternate Names: Gö 6850, Bisindolylmaleimide I

Produktbeschreibung

PKC inhibitor

Produkteigenschaften

• Molekulargewicht: 412.49
• Reinheit: 98% by TLC NMR conforms
• Formulierung: Orange solid
• CAS Nummer: [133052-90-1]
• Formel: C25H24N4O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective protein kinase C inhibitor (IC50 = 10 nM, cAMP-dependent protein kinase IC50 = 2 µM and phosphorylase kinase IC50 = 0.7 µM). Inactive against the tyrosine kinases EGFR, PGDFR and Insulin receptor. Potent inhibitor of GSK-3beta in cell lysates (IC50 = 360nM) and GSK-3beta immunoprecipitates (IC50 = 170nM) derived from rat epididymal adipocytes.2 Cell permeable.