GF-109203X, CAS [[133052-90-1]]

Product Overview

• Article Name: GF-109203X, CAS [[133052-90-1]]
• Biozol Catalog Number: FBM-10-1026
• Supplier Catalog Number: 10-1026
• Alternative Catalog Number: FBM-10-1026-5MG, FBM-10-1026-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide. Alternate Names: Gö 6850, Bisindolylmaleimide I

Product Description

PKC inhibitor

Product Properties

• Molecular Weight: 412.49
• Purity: 98% by TLC NMR conforms
• Form: Orange solid
• CAS Number: [133052-90-1]
• Formula: C25H24N4O2

Application Notes

• Application Notes: Potent and selective protein kinase C inhibitor (IC50 = 10 nM, cAMP-dependent protein kinase IC50 = 2 µM and phosphorylase kinase IC50 = 0.7 µM). Inactive against the tyrosine kinases EGFR, PGDFR and Insulin receptor. Potent inhibitor of GSK-3beta in cell lysates (IC50 = 360nM) and GSK-3beta immunoprecipitates (IC50 = 170nM) derived from rat epididymal adipocytes.2 Cell permeable.