Dorsomorphin, CAS [[866405-64-3]]

Produktübersicht

• Artikelname: Dorsomorphin, CAS [[866405-64-3]]
• Artikelnummer: FBM-10-1029
• Hersteller Artikelnummer: 10-1029
• Alternativnummer: FBM-10-1029-5MG,FBM-10-1029-25MG,FBM-10-1029-10MM/1MLDMSO
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Compound C

Produktbeschreibung

AMPK inhibitor

Produkteigenschaften

• Molekulargewicht: 399.49
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Pale yellow solid
• CAS Nummer: [866405-64-3]
• Formel: C24H25N5O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent, selective and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM).1 It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. It inhibits bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6).2 Dorsomorphin has been shown to promote cardiomyogenesis in mouse embryonic stem cells (ESCs) in vitro.3 Induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.4