Dorsomorphin, CAS [[866405-64-3]]

Product Overview

• Article Name: Dorsomorphin, CAS [[866405-64-3]]
• Biozol Catalog Number: FBM-10-1029
• Supplier Catalog Number: 10-1029
• Alternative Catalog Number: FBM-10-1029-5MG,FBM-10-1029-25MG,FBM-10-1029-10MM/1MLDMSO
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Compound C

Product Description

AMPK inhibitor

Product Properties

• Molecular Weight: 399.49
• Purity: 98% by TLC, NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [866405-64-3]
• Formula: C24H25N5O

Application Notes

• Application Notes: Potent, selective and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM).1 It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. It inhibits bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6).2 Dorsomorphin has been shown to promote cardiomyogenesis in mouse embryonic stem cells (ESCs) in vitro.3 Induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.4