Chemical Name: 4-N-Benzoyl staurosporine. Alternate Names: Midostaurin, CGP-41251
Protein kinase inhib (pan spec.)
Molekulargewicht:
570.65
Reinheit:
98% by TLC, NMR Conforms
Formulierung:
White solid
CAS Nummer:
[120685-11-2]
Formel:
C35H30N4O4
Anwendungsbeschreibung:
Broad spectrum kinase inhibitor. Inhibited kinases include, but are not limited to, PKA, PKC, S6 Kinase, KDR, PKC, Akt, EGFR, VEGFR, PDGFR, c-kit, and FLT-3. Acute myeloid leukemia related mutant forms of FLT-3 are also inhibited both in vitro and in vivo. PKC-412 has been demonstrated to induce apoptosis and shows broad antiproliferative activity in various tumor cell lines. Cell Permeable
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