PKC-412, CAS [[120685-11-2]]

Catalog Number: FBM-10-1105
Article Name: PKC-412, CAS [[120685-11-2]]
Biozol Catalog Number: FBM-10-1105
Supplier Catalog Number: 10-1105
Alternative Catalog Number: FBM-10-1105-5MG, FBM-10-1105-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: 4-N-Benzoyl staurosporine. Alternate Names: Midostaurin, CGP-41251
Protein kinase inhib (pan spec.)
Molecular Weight: 570.65
Purity: 98% by TLC, NMR Conforms
Form: White solid
CAS Number: [120685-11-2]
Formula: C35H30N4O4
Application Notes: Broad spectrum kinase inhibitor. Inhibited kinases include, but are not limited to, PKA, PKC, S6 Kinase, KDR, PKC, Akt, EGFR, VEGFR, PDGFR, c-kit, and FLT-3. Acute myeloid leukemia related mutant forms of FLT-3 are also inhibited both in vitro and in vivo. PKC-412 has been demonstrated to induce apoptosis and shows broad antiproliferative activity in various tumor cell lines. Cell Permeable