WY-14643, CAS [[50892-23-4]]

Produktübersicht

• Artikelname: WY-14643, CAS [[50892-23-4]]
• Artikelnummer: FBM-10-1137
• Hersteller Artikelnummer: 10-1137
• Alternativnummer: FBM-10-1137-50MG, FBM-10-1137-250MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid. Alternate Names: Pirinixic acid

Produktbeschreibung

PPARalpha agonist

Produkteigenschaften

• Molekulargewicht: 323.80
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [50892-23-4]
• Formel: C14H14ClN2O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Selective PPARalpha agonist (EC50=0.63, 32 and >100 µM for PPARalpha,gamma and delta, respectively).1 Displays anti-inflammatory activity2 and reduces LPS-induced inflammation in alveolar epithelial cells3. Induces ''browning of white adipocytes in combined treatment with retinoic acid.4 Stimulates ADAM10-mediated proteolysis of amyloid precursor protein in a mouse model.5 Down regulates NFkappaB transcriptional activity. Review.6