WY-14643, CAS [[50892-23-4]]

Product Overview

• Article Name: WY-14643, CAS [[50892-23-4]]
• Biozol Catalog Number: FBM-10-1137
• Supplier Catalog Number: 10-1137
• Alternative Catalog Number: FBM-10-1137-50MG, FBM-10-1137-250MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid. Alternate Names: Pirinixic acid

Product Description

PPARalpha agonist

Product Properties

• Molecular Weight: 323.80
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [50892-23-4]
• Formula: C14H14ClN2O2S

Application Notes

• Application Notes: Selective PPARalpha agonist (EC50=0.63, 32 and >100 µM for PPARalpha,gamma and delta, respectively).1 Displays anti-inflammatory activity2 and reduces LPS-induced inflammation in alveolar epithelial cells3. Induces ''browning of white adipocytes in combined treatment with retinoic acid.4 Stimulates ADAM10-mediated proteolysis of amyloid precursor protein in a mouse model.5 Down regulates NFkappaB transcriptional activity. Review.6