P7C3, CAS [[301353-96-8]]

Produktübersicht

• Artikelname: P7C3, CAS [[301353-96-8]]
• Artikelnummer: FBM-10-1150
• Hersteller Artikelnummer: 10-1150
• Alternativnummer: FBM-10-1150-5MG, FBM-10-1150-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol

Produktbeschreibung

Neuroprotective

Produkteigenschaften

• Molekulargewicht: 474.20
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [301353-96-8]
• Formel: C21H18Br2N2O

Anwendungsbeschreibung

• Anwendungsbeschreibung: P7C3 exerts proneurogenic activity by protecting newborn neurons from apoptosis. Prolonged administration to aged rats impedes neuronal death and preserves cognitive capacity.1 Delays disease progression in G93A-SOD2 mutant mouse model of amyotrophic lateral sclerosis.2 Blocks MPTP-mediated cell death of dopaminergic neurons in the substantia nigra of adult mice, a model of Parkinson disease.3 Restores hippocampal neurogenesis in a mouse model of Down Syndrome.4 The mechanism of action involves activation of nicotinamide phosphoribosyltransferase (NAMPT) with concomitant increase of intracellular levels of NAD.5 Active in vivo.