P7C3, CAS [[301353-96-8]]

Product Overview

• Article Name: P7C3, CAS [[301353-96-8]]
• Biozol Catalog Number: FBM-10-1150
• Supplier Catalog Number: 10-1150
• Alternative Catalog Number: FBM-10-1150-5MG, FBM-10-1150-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol

Product Description

Neuroprotective

Product Properties

• Molecular Weight: 474.20
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [301353-96-8]
• Formula: C21H18Br2N2O

Application Notes

• Application Notes: P7C3 exerts proneurogenic activity by protecting newborn neurons from apoptosis. Prolonged administration to aged rats impedes neuronal death and preserves cognitive capacity.1 Delays disease progression in G93A-SOD2 mutant mouse model of amyotrophic lateral sclerosis.2 Blocks MPTP-mediated cell death of dopaminergic neurons in the substantia nigra of adult mice, a model of Parkinson disease.3 Restores hippocampal neurogenesis in a mouse model of Down Syndrome.4 The mechanism of action involves activation of nicotinamide phosphoribosyltransferase (NAMPT) with concomitant increase of intracellular levels of NAD.5 Active in vivo.