Synaptamide, CAS [[162758-94-3]]

Artikelnummer: FBM-10-1194
Artikelname: Synaptamide, CAS [[162758-94-3]]
Artikelnummer: FBM-10-1194
Hersteller Artikelnummer: 10-1194
Alternativnummer: FBM-10-1194-5MG,FBM-10-1194-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: DHA-ethanolamide
Endogenous agonist at GPR110
Molekulargewicht: 371.56
Reinheit: 98% by TLC, NMR (Conforms)
Formulierung: Colorless to yellow oil
CAS Nummer: [162758-94-3]
Formel: C24H37NO2
Anwendungsbeschreibung: Anandamide-like lipid mediator produced from DHA in the brain. Stimulates neurite growth, synaptogenesis and glutamatergic synaptic activity in developing hippocampal neurons at 10-100 nM.1 Potently induces neuronal differentiation of neural stem cells.2 Promotes growth of cortical axons vial modulation of hedgehog signaling.3 Binds to and activates orphan receptor GPR110, stimulating cAMP production at low nM concentrations.4 Reduces LPS-induced TNFalpha production in cultured microglia cells and ameliorates LPS-induced neuroinflammation in a mouse model.5