Synaptamide, CAS [[162758-94-3]]

Product Overview

• Article Name: Synaptamide, CAS [[162758-94-3]]
• Biozol Catalog Number: FBM-10-1194
• Supplier Catalog Number: 10-1194
• Alternative Catalog Number: FBM-10-1194-5MG,FBM-10-1194-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: DHA-ethanolamide

Product Description

Endogenous agonist at GPR110

Product Properties

• Molecular Weight: 371.56
• Purity: 98% by TLC, NMR (Conforms)
• Form: Colorless to yellow oil
• CAS Number: [162758-94-3]
• Formula: C24H37NO2

Application Notes

• Application Notes: Anandamide-like lipid mediator produced from DHA in the brain. Stimulates neurite growth, synaptogenesis and glutamatergic synaptic activity in developing hippocampal neurons at 10-100 nM.1 Potently induces neuronal differentiation of neural stem cells.2 Promotes growth of cortical axons vial modulation of hedgehog signaling.3 Binds to and activates orphan receptor GPR110, stimulating cAMP production at low nM concentrations.4 Reduces LPS-induced TNFalpha production in cultured microglia cells and ameliorates LPS-induced neuroinflammation in a mouse model.5