IU1, CAS [[314245-33-5]]

Produktübersicht

• Artikelname: IU1, CAS [[314245-33-5]]
• Artikelnummer: FBM-10-1197
• Hersteller Artikelnummer: 10-1197
• Alternativnummer: FBM-10-1197-10MG,FBM-10-1197-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

USP14 inhibitor

Produkteigenschaften

• Molekulargewicht: 300.38
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Beige solid
• CAS Nummer: [314245-33-5]
• Formel: C18H21FN2O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Selective inhibitor of Usp14 (IC50<4 µM). Enhances proteasome activity and substrate proteolysis.1,2 Inhibits Dengue virus replication.3 In prion-infected CAD5 cells activation of the ubiquitin proteasome system by IU1 is sufficient to induce clearance of polyubiquitinated substrates and reduce misfolded prion protein load.4 Attenuates ischemia/reperfusion-induced neuronal injury in a mouse model.5 Cell permeable.