IU1, CAS [[314245-33-5]]

Product Overview

• Article Name: IU1, CAS [[314245-33-5]]
• Biozol Catalog Number: FBM-10-1197
• Supplier Catalog Number: 10-1197
• Alternative Catalog Number: FBM-10-1197-10MG, FBM-10-1197-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone

Product Description

USP14 inhibitor

Product Properties

• Molecular Weight: 300.38
• Purity: 98% by TLC, NMR (Conforms)
• Form: Beige solid
• CAS Number: [314245-33-5]
• Formula: C18H21FN2O

Application Notes

• Application Notes: Selective inhibitor of Usp14 (IC50<4 µM). Enhances proteasome activity and substrate proteolysis.1,2 Inhibits Dengue virus replication.3 In prion-infected CAD5 cells activation of the ubiquitin proteasome system by IU1 is sufficient to induce clearance of polyubiquitinated substrates and reduce misfolded prion protein load.4 Attenuates ischemia/reperfusion-induced neuronal injury in a mouse model.5 Cell permeable.