Selective activator of protein kinase C which displays antileukemic activity mediated via PKC1 In contrast, it provides a strong survival signal to resting and activated human T cells via activation of PKC and downstream activation of NFB.2 Treatment of subcutaneous tumors results in anti-cancer CD8 T cells, also displays adjuvant activity and synergizes with cancer immunotherapies.3 Induces senescence-like growth arrest in solid tumor cells.4 Inhibits HIV-1 infection at an early pathway of viral entry.5
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