Ingenol-3-angelate, CAS [[75567-37-2]]

Product Overview

• Article Name: Ingenol-3-angelate, CAS [[75567-37-2]]
• Biozol Catalog Number: FBM-10-1244
• Supplier Catalog Number: 10-1244
• Alternative Catalog Number: FBM-10-1244-1MG,FBM-10-1244-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: PEP-005

Product Description

PKC activator

Product Properties

• Molecular Weight: 460.53
• Purity: 98% by TLC NMR (Conforms)
• Form: White solid
• CAS Number: [75567-37-2]
• Formula: C25H34O6

Application Notes

• Application Notes: Selective activator of protein kinase C which displays antileukemic activity mediated via PKC1 In contrast, it provides a strong survival signal to resting and activated human T cells via activation of PKC and downstream activation of NFB.2 Treatment of subcutaneous tumors results in anti-cancer CD8 T cells, also displays adjuvant activity and synergizes with cancer immunotherapies.3 Induces senescence-like growth arrest in solid tumor cells.4 Inhibits HIV-1 infection at an early pathway of viral entry.5