Cytarabine, CAS [[147-94-4]]

Produktübersicht

• Artikelname: Cytarabine, CAS [[147-94-4]]
• Artikelnummer: FBM-10-1268
• Hersteller Artikelnummer: 10-1268
• Alternativnummer: FBM-10-1268-500MG, FBM-10-1268-2G
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone. Alternate Names: Arabinocytidine, Cytosine beta-D-Arabinofuranoside, U-19920A, Ara-C

Produktbeschreibung

DNA synthesis and transcription disruptor

Produkteigenschaften

• Molekulargewicht: 243.22
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [147-94-4]
• Formel: C9H13N3O5

Anwendungsbeschreibung

• Anwendungsbeschreibung: A nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells.1,2 It Cellular enzymes convert it to its nucleotide form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it.3,4 For the same reasons, it is also employed as an antiviral.5 It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML).6,7