MG-132, CAS [[133407-82-6]]

Produktübersicht

• Artikelname: MG-132, CAS [[133407-82-6]]
• Artikelnummer: FBM-10-1309
• Hersteller Artikelnummer: 10-1309
• Alternativnummer: FBM-10-1309-5MG,FBM-10-1309-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Z-Leu-Leu-Leu-CHO

Produktbeschreibung

Proteasome inhibitor

Produkteigenschaften

• Molekulargewicht: 475.63
• Reinheit: 98% by HPLC
• Formulierung: White solid
• CAS Nummer: [133407-82-6]
• Formel: C26H41N3O5

Anwendungsbeschreibung

• Anwendungsbeschreibung: Specific inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50=100 nM with Z-LLL-AMC as substrate).1 Also inhibits calpain (IC50=1.25 µM)1 Suppresses gastric cancer cell proliferation and induces macro-autophagy2. Activates stress kinases and induces Hsp72.3 Induces neurite outgrowth.1 Blocks NFkappaB activation by blocking IkappaB proteolysis (IC50=3 µM).4 Cell permeable.