MG-132, CAS [[133407-82-6]]

Product Overview

• Article Name: MG-132, CAS [[133407-82-6]]
• Biozol Catalog Number: FBM-10-1309
• Supplier Catalog Number: 10-1309
• Alternative Catalog Number: FBM-10-1309-5MG, FBM-10-1309-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-(Benzyloxycarbonyl)leucinylleucinylleucinal. Alternate Names: Z-Leu-Leu-Leu-CHO

Product Description

Proteasome inhibitor

Product Properties

• Molecular Weight: 475.63
• Purity: 98% by HPLC
• Form: White solid
• CAS Number: [133407-82-6]
• Formula: C26H41N3O5

Application Notes

• Application Notes: Specific inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50=100 nM with Z-LLL-AMC as substrate).1 Also inhibits calpain (IC50=1.25 µM)1 Suppresses gastric cancer cell proliferation and induces macro-autophagy2. Activates stress kinases and induces Hsp72.3 Induces neurite outgrowth.1 Blocks NFkappaB activation by blocking IkappaB proteolysis (IC50=3 µM).4 Cell permeable.