FH-535, CAS [[108409-83-2]]

Produktübersicht

• Artikelname: FH-535, CAS [[108409-83-2]]
• Artikelnummer: FBM-10-1328
• Hersteller Artikelnummer: 10-1328
• Alternativnummer: FBM-10-1328-10MG,FBM-10-1328-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Wnt/beta-cantenin inhibitor

Produkteigenschaften

• Molekulargewicht: 361.21
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Tan solid
• CAS Nummer: [108409-83-2]
• Formel: C13H10Cl2N2O4S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Suppresses Wnt/beta-catenin signaling. It antagonizes PPARgamma and PPARdelta ligand-dependent activation which is mediated by inhibition of recruitment of the coactivators beta-catenin and GRIP1 but not the corepressors NCoR and SMRT1. Inhibits the migration and growth of breast cancer cell lines2 as well as colon, lung and liver cell lines1. Useful tool for probing the involvement of Wnt signaling pathway3,4.