FH-535, CAS [[108409-83-2]]

Product Overview

• Article Name: FH-535, CAS [[108409-83-2]]
• Biozol Catalog Number: FBM-10-1328
• Supplier Catalog Number: 10-1328
• Alternative Catalog Number: FBM-10-1328-10MG,FBM-10-1328-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Wnt/beta-cantenin inhibitor

Product Properties

• Molecular Weight: 361.21
• Purity: 98% by TLC, NMR (Conforms)
• Form: Tan solid
• CAS Number: [108409-83-2]
• Formula: C13H10Cl2N2O4S

Application Notes

• Application Notes: Suppresses Wnt/beta-catenin signaling. It antagonizes PPARgamma and PPARdelta ligand-dependent activation which is mediated by inhibition of recruitment of the coactivators beta-catenin and GRIP1 but not the corepressors NCoR and SMRT1. Inhibits the migration and growth of breast cancer cell lines2 as well as colon, lung and liver cell lines1. Useful tool for probing the involvement of Wnt signaling pathway3,4.