C16, CAS [[608512-97-6]]

Produktübersicht

• Artikelname: C16, CAS [[608512-97-6]]
• Artikelnummer: FBM-10-1329
• Hersteller Artikelnummer: 10-1329
• Alternativnummer: FBM-10-1329-5MG, FBM-10-1329-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one

Produktbeschreibung

PKR inhibitor

Produkteigenschaften

• Molekulargewicht: 268.30
• Reinheit: 98% by TLC, NMR Conforms
• Formulierung: Orange solid
• CAS Nummer: [608512-97-6]
• Formel: C13H8N4OS

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibits RNA-dependent protein kinase (PKR, IC50 = 210 nM)1. Inhibits ER stress-induced neuronal damage2. Reduces brain PKR activation in vivo3. Prevents apoptosis and IL-1beta production in an acute excitotoxic and neuroinflammatory rat model4. Prevents beta-amyloid peptide-induced inflammation in primary murine mixed co-cultures5. Cell permeable.