b-AP15 (NSC-687852), CAS [[1009817-63-3]]

Produktübersicht

• Artikelname: b-AP15 (NSC-687852), CAS [[1009817-63-3]]
• Artikelnummer: FBM-10-1340
• Hersteller Artikelnummer: 10-1340
• Alternativnummer: FBM-10-1340-5MG, FBM-10-1340-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3,5-bis[(4-Nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one. Alternate Names: NSC-687852

Produktbeschreibung

DUB inhibitor

Produkteigenschaften

• Molekulargewicht: 419.40
• Reinheit: >98% by HPLC
• Formulierung: Pale yellow solid. (MP = 170-174C)
• CAS Nummer: [1009817-63-3]
• Formel: C22H17N3O6

Anwendungsbeschreibung

• Anwendungsbeschreibung: Abrogates the deubiquitinating activity of the 19S regulatory particle by inhibiting ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) resulting in accumulation of polyubiquitin in cells. b-AP15 induces tumor cell apoptosis and tumor progression in four different solid tumor models in vivo.