Spautin-1, CAS [[1262888-28-7]]

Produktübersicht

• Artikelname: Spautin-1, CAS [[1262888-28-7]]
• Artikelnummer: FBM-10-1367
• Hersteller Artikelnummer: 10-1367
• Alternativnummer: FBM-10-1367-5MG,FBM-10-1367-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Inhibits autophagy by inhibiting USP 10 and 13

Produkteigenschaften

• Molekulargewicht: 271.27
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Tan solid
• CAS Nummer: [1262888-28-7]
• Formel: C15H11F2N3

Anwendungsbeschreibung

• Anwendungsbeschreibung: A specific and potent autophagy inhibitor. Spautin-1 promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin-specific proteases USP10 and USP13 which target the Beclin-1 subunit of Vps34 complexes1. Deranges dengue virion maturation2. Inhibits autophagy in a Beclin-1 independent manner in primary epithelial ovarian cancer cells3. Selectively induces cell death of mutant p53-expressing cancer cell lines under confluency4. Cell permeable.