AG-1517 HCl, CAS [[153436-54-5]]

Produktübersicht

• Artikelname: AG-1517 HCl, CAS [[153436-54-5]]
• Artikelnummer: FBM-10-1377
• Hersteller Artikelnummer: 10-1377
• Alternativnummer: FBM-10-1377-5MG,FBM-10-1377-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: PD153,053, SU-5271, Z-252868

Produktbeschreibung

Tyrosine kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 360.21
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: white or off-white solid
• CAS Nummer: [153436-54-5]
• Formel: C16H14BrN3O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation1. Inhibits the growth of a number of cancer cell lines2. An extremely useful tool for exploring EGF-mediated cellular signaling3.