LM22A-4, CAS [[37988-18-4]]

Produktübersicht

• Artikelname: LM22A-4, CAS [[37988-18-4]]
• Artikelnummer: FBM-10-1405
• Hersteller Artikelnummer: 10-1405
• Alternativnummer: FBM-10-1405-5MG,FBM-10-1405-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

TrkB agonist

Produkteigenschaften

• Molekulargewicht: 339.35
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [37988-18-4]
• Formel: C15H21N3O6

Anwendungsbeschreibung

• Anwendungsbeschreibung: Small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, it caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats1. Improves respiratory function in a mouse models of Rett syndrome2.