LM22A-4, CAS [[37988-18-4]]

Product Overview

• Article Name: LM22A-4, CAS [[37988-18-4]]
• Biozol Catalog Number: FBM-10-1405
• Supplier Catalog Number: 10-1405
• Alternative Catalog Number: FBM-10-1405-5MG, FBM-10-1405-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N,NN Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide

Product Description

TrkB agonist

Product Properties

• Molecular Weight: 339.35
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [37988-18-4]
• Formula: C15H21N3O6

Application Notes

• Application Notes: Small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, it caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats1. Improves respiratory function in a mouse models of Rett syndrome2.