BMS-303141, CAS [[943962-47-8]]

Produktübersicht

• Artikelname: BMS-303141, CAS [[943962-47-8]]
• Artikelnummer: FBM-10-1414
• Hersteller Artikelnummer: 10-1414
• Alternativnummer: FBM-10-1414-5MG, FBM-10-1414-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1-biphenyl]-3-yl)-benzenesulfonamide. Alternate Names: ACLYi

Produktbeschreibung

ATP citrate lyase (ACL) inhibitor

Produkteigenschaften

• Molekulargewicht: 424.30
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [943962-47-8]
• Formel: C19H15Cl2NO4S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 M. Inhibits lipid biosynthesis, IC50=8 M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4