CZC-54252, CAS [[1191911-27-9]]

Produktübersicht

• Artikelname: CZC-54252, CAS [[1191911-27-9]]
• Artikelnummer: FBM-10-1421
• Hersteller Artikelnummer: 10-1421
• Alternativnummer: FBM-10-1421-5MG, FBM-10-1421-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[[[5-Chloro-2-[[2-methoxy-4-(4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-phenyl]methanesulfonamide hydrochloride

Produktbeschreibung

LRRK2

Produkteigenschaften

• Molekulargewicht: 541.46
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1191911-27-9]
• Formel: C22H25ClN6O4S HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: Novel, potent and selective inhibitor of the leucine-rich repeat kinase-2 (LRRK2), IC50 = 1.28 nM. Also inhibits G2019S mutant LRRK2, IC50 = 1.85 nM1. Attenuates the neuronal damage elicited by the action of LRRK2 G2019S mutant in primary human neurons (EC50 = 1 nM)1. The G2019S mutant is a common mutation found in familial Parkinsons disease patients2. Cell permeable.