Gue1654, CAS [[397290-30-1]]

Produktübersicht

• Artikelname: Gue1654, CAS [[397290-30-1]]
• Artikelnummer: FBM-10-1425
• Hersteller Artikelnummer: 10-1425
• Alternativnummer: FBM-10-1425-5MG, FBM-10-1425-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[7-(Methylthio)benzo[1,2-d:4,3-d]bisthiazol-2-yl]-alpha-phenylbenzeneacetamide

Produktbeschreibung

OXE-R biased antagonist

Produkteigenschaften

• Molekulargewicht: 447.59
• Reinheit: >98% by TLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [397290-30-1]
• Formel: C23H17N3OS3

Anwendungsbeschreibung

• Anwendungsbeschreibung: Gue1654 is a biased antagonist for the oxoeicosanoid receptor 1 (OXE-R, GPR170)1, the receptor for 5-Oxo-ETE, a proinflammatory eicosanoid2. It selectively inhibits Gbetagamma but not Galphai signaling upon activation of the Galphai-betagamma heterotrimer by OXE-R.1,3 Gue1654 alleviated coronary artery ligation-induced ischemic myocardial injury in a mouse model.4