ML297, CAS [[1443246-62-5]]

Produktübersicht

• Artikelname: ML297, CAS [[1443246-62-5]]
• Artikelnummer: FBM-10-1469
• Hersteller Artikelnummer: 10-1469
• Alternativnummer: FBM-10-1469-5MG, FBM-10-1469-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-(3.4-Difluorophenyl)-n-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea. Alternate Names: VU0456810

Produktbeschreibung

GIRK activator

Produkteigenschaften

• Molekulargewicht: 328.32
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1443246-62-5]
• Formel: C17H14F2N4O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Selective GIRK (Kir3.1/3.2) channel activator, IC50 = 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively. Has no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels.1,2 Displays antiseizure activity2 and decreases anxiety-related behavior without sedative or addictive effects3. Reduces glucose- and IBMX-stimulated GLP-1 secretion with no effect on GIP in murine L and K cells.4 Brain penetrant.