YM-155, CAS [[781661-94-7]]

Produktübersicht

• Artikelname: YM-155, CAS [[781661-94-7]]
• Artikelnummer: FBM-10-1473
• Hersteller Artikelnummer: 10-1473
• Alternativnummer: FBM-10-1473-5MG,FBM-10-1473-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Sepantronium bromide

Produktbeschreibung

Survivin inhibitor

Produkteigenschaften

• Molekulargewicht: 443.30
• Reinheit: >98% by TLC NMR (Conforms)
• Formulierung: Tan to yellow solid
• CAS Nummer: [781661-94-7]
• Formel: C20H19BrN4O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4