Indirubin-3-monoxime, CAS [[160807-49-8]]

Produktübersicht

• Artikelname: Indirubin-3-monoxime, CAS [[160807-49-8]]
• Artikelnummer: FBM-10-1488
• Hersteller Artikelnummer: 10-1488
• Alternativnummer: FBM-10-1488-5MG, FBM-10-1488-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-[1,3-Dihydro-3-(hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one. Alternate Names: Indirubin-3oxime

Produktbeschreibung

GSK-3b and CDK inhibitor

Produkteigenschaften

• Molekulargewicht: 277.29
• Reinheit: 98% by TLC, NMR (conforms)
• Formulierung: Dark red or brown solid
• CAS Nummer: [160807-49-8]
• Formel: C16H11N3O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A potent GSK-3beta inhibitor (IC50=22 nM)1. Also inhibits CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM)1. Displays antimitotic properties and induces endoreplication following prophase arrest in HBL-100 cells2. Possesses antiangiogenic activity3. Attenuates beta-amyloid-associated neuropathology in a mouse model of Alzheimers disease4. Cell permeable.