Indirubin-3-monoxime, CAS [[160807-49-8]]

Product Overview

• Article Name: Indirubin-3-monoxime, CAS [[160807-49-8]]
• Biozol Catalog Number: FBM-10-1488
• Supplier Catalog Number: 10-1488
• Alternative Catalog Number: FBM-10-1488-5MG, FBM-10-1488-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-[1,3-Dihydro-3-(hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one. Alternate Names: Indirubin-3oxime

Product Description

GSK-3b and CDK inhibitor

Product Properties

• Molecular Weight: 277.29
• Purity: 98% by TLC, NMR (conforms)
• Form: Dark red or brown solid
• CAS Number: [160807-49-8]
• Formula: C16H11N3O2

Application Notes

• Application Notes: A potent GSK-3beta inhibitor (IC50=22 nM)1. Also inhibits CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM)1. Displays antimitotic properties and induces endoreplication following prophase arrest in HBL-100 cells2. Possesses antiangiogenic activity3. Attenuates beta-amyloid-associated neuropathology in a mouse model of Alzheimers disease4. Cell permeable.