AI-3, CAS [[882288-28-0]]

Produktübersicht

• Artikelname: AI-3, CAS [[882288-28-0]]
• Artikelnummer: FBM-10-1497
• Hersteller Artikelnummer: 10-1497
• Alternativnummer: FBM-10-1497-5MG, FBM-10-1497-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one

Produktbeschreibung

ARE activator

Produkteigenschaften

• Molekulargewicht: 292.81
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: white solid MP = 71-74C
• CAS Nummer: [882288-28-0]
• Formel: C11H13ClO3S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at Cys151 and is reactive toward additional cysteines at higher concentrations. Disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Cell permeable and active in vivo.