STF-083010, CAS [[307543-71-1]]

Produktübersicht

• Artikelname: STF-083010, CAS [[307543-71-1]]
• Artikelnummer: FBM-10-1510
• Hersteller Artikelnummer: 10-1510
• Alternativnummer: FBM-10-1510-5MG, FBM-10-1510-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide

Produktbeschreibung

IRE1 ribonuclease inhibitor

Produkteigenschaften

• Molekulargewicht: 317.39
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: yellow solid
• CAS Nummer: [307543-71-1]
• Formel: C15H11NO3S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo.