Fascaplysin, CAS [[114719-57-2]]

Produktübersicht

• Artikelname: Fascaplysin, CAS [[114719-57-2]]
• Artikelnummer: FBM-10-1517
• Hersteller Artikelnummer: 10-1517
• Alternativnummer: FBM-10-1517-1MG, FBM-10-1517-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 12,13-Dihydro-13-oxopyrido[1,2-a:3,4-b]diindol-5-ium chloride

Produktbeschreibung

CDK4 inhibitor

Produkteigenschaften

• Molekulargewicht: 306.75
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Dark red-brown solid
• CAS Nummer: [114719-57-2]
• Formel: C18H11ClN2O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 µM) and is less selective for Cdk6/D1 (IC50 = 3.4 µM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.