GW-501516, CAS [[317318-70-0]]

Produktübersicht

• Artikelname: GW-501516, CAS [[317318-70-0]]
• Artikelnummer: FBM-10-1542
• Hersteller Artikelnummer: 10-1542
• Alternativnummer: FBM-10-1542-5MG, FBM-10-1542-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazoyl]methyl]thio]phenoxy]acetic acid

Produktbeschreibung

PPARdelta agonist

Produkteigenschaften

• Molekulargewicht: 453.50
• Reinheit: 98% by TLC NMr (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [317318-70-0]
• Formel: C21H18F3NO3S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective PPARdelta (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance.2 Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation.3 Upregulates human Sirt1 via Sp1 activation.4 Along with exercise, GW-501516 synergistically increases running endurance.5