GW-501516, CAS [[317318-70-0]]

Product Overview

• Article Name: GW-501516, CAS [[317318-70-0]]
• Biozol Catalog Number: FBM-10-1542
• Supplier Catalog Number: 10-1542
• Alternative Catalog Number: FBM-10-1542-5MG, FBM-10-1542-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazoyl]methyl]thio]phenoxy]acetic acid

Product Description

PPARdelta agonist

Product Properties

• Molecular Weight: 453.50
• Purity: 98% by TLC NMr (Conforms)
• Form: Off-white solid
• CAS Number: [317318-70-0]
• Formula: C21H18F3NO3S2

Application Notes

• Application Notes: Potent and selective PPARdelta (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance.2 Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation.3 Upregulates human Sirt1 via Sp1 activation.4 Along with exercise, GW-501516 synergistically increases running endurance.5